The College of Nursing continues to be among the best performing schools in the country, consistently topping the national board exams. It was recognized by the Commission on Higher Education in 1992 and graduated its first batch in 1993.  The first board takers immediately pinned a 100% passing rate in the Integrated Nurses Licensure Examination.

The four-year Bachelor of Science in Nursing Program is community-oriented, revolving around the promotion of health, prevention of illness, and  rehabilitation of clients in the communities.  The College commits to an education responsive to the needs and goals of the community and the country.  It provides opportunities for students to involve in community activities and services that promote their physical and spiritual fitness, cultural and environmental consciousness, and sense of national identity.

With the vision to produce health workers with preference for the poor and marginalized in the region, students engage in basic sanitation activities in the community such as the regular free circumcisions in barangays.  A course requirement also provides opportunities for students to share their expertise in particular health issues through community fora and informal discussions. Students also devote time to community health centers or hospitals before graduating. 

Xavier University shall strive to remain the country's leading provider of quality nursing education  to help Filipinos both local and global clientele the best health service in the world.